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Pharmaceutical Executive

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News

PharmExec
pharmexec.com > view > zeno-paradox-orphan-product-access-future-unmet-need

Zeno???s Paradox, Orphan Product Access and the Future of Unmet Need

3+ day, 7+ hour ago   (364+ words) Unmet need is likely a new battlefield impacting prior authorization. CMS ACCESS Model: Changing the Landscape of Disease Management Orphan Product Risk Contracting Future Phase III Trial Planning: Payer Point of View Zeno’s paradox is a riddle about motion and…...

PharmExec
pharmexec.com > view > agentic-ai-revolution-biopharma

The Agentic AI Revolution in Biopharma

3+ day, 8+ hour ago   (1556+ words) How agentic artificial intelligence is transforming the value chain from discovery to commercialization. The biopharmaceutical industry is undergoing a profound transformation, driven by the emergence of agentic artificial intelligence (AI). Unlike traditional AI models that require continuous human guidance, agentic…...

PharmExec
pharmexec.com > view > practical-testing-methods-high-cortisol-levels

Practical Testing Methods for High Cortisol Levels

3+ day, 13+ hour ago   (187+ words) Dr. Elena Christofides on why the overnight dexamethasone suppression test is the only cortisol screen that actually identifies HPA dysfunction. GLP-1 medications might be most well-known as weight-loss options, but they were originally developed as a treatment for type 2 diabetes....

PharmExec
pharmexec.com > view > life-sciences-companies-real-impact-patient-engagement

How Life Sciences Companies Can Create Real Impact With Patient Engagement

3+ day, 13+ hour ago   (165+ words) A “maturity curve” can help organizations move engagement beyond performative gestures to a strategic asset. For more than 20 years now, companies in the life sciences industry have waved the banner of patient-centricity, spending on advisory boards, listening sessions and even…...

PharmExec
pharmexec.com > view > artisan-calls-novartis-board-shake-up

Artisan Partners??? Director Calls for Novartis Board Shake-Up

3+ day, 14+ hour ago   (362+ words) Artisan Partners' David Samra is publicly calling for Novartis to overhaul its board and compensation structure following back-to-back trial failures. A major shareholder in Novartis calls for a shake-up of the Swiss drugmaker's board to improve corporate governance, after the…...

PharmExec
pharmexec.com > view > hhs-confirms-four-senior-fda-leaders-including-agency-first-ai-deputy-commissioner

HHS Confirms Four Senior FDA Leaders, Including Agency's First-Ever AI Deputy Commissioner

4+ day, 15+ hour ago   (449+ words) Pharmaceutical Executive...

PharmExec
pharmexec.com > view > kura-oncology-spins-out-caspian-therapeutics-50-million-test-menin-inhibition-as-a-disease-modifying-approach-diabetes

Kura Oncology Spins Out Caspian Therapeutics With $50 Million to Test Menin Inhibition as a Disease-Modifying Approach to Diabetes

4+ day, 15+ hour ago   (200+ words) Kura Oncology spins out Caspian Therapeutics to apply its menin inhibitor expertise to diabetes — with Eli Lilly validating the science. The financing is designed to fund KO-7246 — a next-generation, highly selective oral menin inhibitor purpose-built for chronic metabolic disease — through…...

PharmExec
pharmexec.com > view > ibd-most-persistent-gap-christian-thienel

IBD's Most Persistent Gap: Q&A with Christian Thienel

4+ day, 20+ hour ago   (394+ words) Back Bay’s director discusses why IBD remains underserved — JAK inhibitor constraints, emerging oral mechanisms, and the durability gap. In 2024, Pharmaceutical Executive reported on a survey that showed a significant number of patients suffering from irritable bowel disease (IBD) struggle to…...

Pharmaceutical Executive
pharmexec.com > shorts > unlocking-future-real-world-data-research

Unlocking the Future of Real-World Data & Research | PharmExec

4+ day, 20+ hour ago   (40+ words) Unlocking the Future of Real-World Data & Research Pharmaceutical Executive Pharmaceutical Executive Daily: Moonwalk Biosciences' $70 Million Series B Trusted Research Environments Are Reshaping Real-World Data Access: Q&A with Mark Cziraky FDA Approves Zanvastro for Alexander Disease in Pediatrics & Adults...

PharmExec
pharmexec.com > view > elevated-cortisol-levels-impact-type-ii-diabetes-treatments

How Elevated Cortisol Levels Can Impact Type II Diabetes Treatments

4+ day, 20+ hour ago   (218+ words) Dr. Elena Christofides on why cortisol dysregulation may explain why so many patients fail to respond to GLP-1 and incretin therapies. GLP-1 medications might be most well-known as weight-loss options, but they were originally developed as a treatment for type…...